Stem cells in the gingiva may have important medical applications in the future
Aug 7th, 2013 · Comments Off
Main Category: Dentistry
Also Included In: Stem Cell Research; Immune System / Vaccines
Article Date: 07 Aug 2013 – 1:00 PDT
University of Southern California
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MLA
Gingivae Contain Neural-crest- and Mesoderm-derived Mesenchymal Stem Cells
X. Xu,
C. Chen,
K. Akiyama,
Y. Chai,
A.D. Le,
Z. Wang,
and S. Shi
“Through the study of this unique oral tissue, we want to shed the light on the translational applications for improving skin wound healing and reducing scar formation.”
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The study indicates that the stem cells in the gingiva – obtained via a simple biopsy of the gums – may have important medical applications in the future.
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Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in the Journal of Dental Research.
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University of Southern California. “Stem cells in the gingiva may have important medical applications in the future.” Medical News Today. MediLexicon, Intl., 7 Aug. 2013. Web.
7 Aug. 2013. <http://www.medicalnewstoday.com/releases/264450.php>
“Gingiva is very unique in our body,” says Professor Songtao Shi, the study’s senior author. “It has much less inflammatory reaction and heals much faster when compared to skin.”
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Journal of Dental Research, doi: 10.1177/0022034513497961, first published on July 18, 2013
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APA
The two types of stem cells vary dramatically in their abilities. N-GMSC were not only easier to change into other types of cells, including neural and cartilage-producing cells; they also had much more of a healing effect on inflammatory disease than their counterparts. When the N-GMSC were transplanted into mice with dextrate sulfate sodium-induced colitis – an inflamed condition of the colon – the inflammation was significantly reduced.
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“We will further work on dissecting the details of the gingiva stem cells, especially their notable immunoregulatory property,” says first author Xingtian Xu, specialized lab technician at the Ostrow School of Dentistry Center for Craniofacial Molecular Biology.
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Stem cells in the gingiva may have important medical applications in the future