New recombinant antibody can isolate stem cells from umbilical cord blood

Main Category: Stem Cell Research
Article Date: 05 Sep 2013 – 1:00 PDT

Contact Our News Editors


“The authors have used antibody phage display technology to generate an anti-i antibody,” says BioResearch Open Access Editor Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland. “The advantage of this technique is that antibodies against poorly immunogenic molecules can be generated, as an immunization strategy is not required. The availability of an anti-i antibody has the potential to improve the isolation efficiency of MSCs from umbilical cord blood samples.”

Current ratings for:
New recombinant antibody can isolate stem cells from umbilical cord blood

In the article “Production of a Recombinant Antibody Specific for i Blood Group Antigen, a Mesenchymal Stem Cell Marker,” the authors explain that the i antigen can serve as a marker to detect and isolate MSCs in umbilical cord blood (UCB). They describe the use of antibody phage display technology to produce a recombinant anti-i antibody that recognizes i antigen on the surface of UCB-MSCs as well as on red blood cells.

Liebert, Mary Ann. “New recombinant antibody can isolate stem cells from umbilical cord blood.” Medical News Today. MediLexicon, Intl., 5 Sep. 2013. Web.
5 Sep. 2013. <http://www.medicalnewstoday.com/releases/265644.php>

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders. The antibody recognizes an i blood group antigen present on MSCs in umbilical cord blood, as described in a study published in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

stem cell research section for the latest news on this subject.

Please use one of the following formats to cite this article in your essay, paper or report:

For any corrections of factual information, or to contact the editors please use our feedback form.

Please send any medical news or health news press releases to:

MLA


APA


Tia Hirvonen and coauthors from the Finnish Red Cross Blood Service, Glykos Finland Ltd., and Biova Ltd. (Helsinki), and VTT Technical Research Center of Finland (Espoo), identified a blood donor with high levels of antibody to the i blood group antigen. No antibodies recognizing this antigen are commercially available at present.



privacy policy for more information.

“Production of a Recombinant Antibody Specific for i Blood Group Antigen, a Mesenchymal Stem Cell Marker” Tia Hirvonen, Heli Suila, Sari Tiitinen, Suvi Natunen, Marja-Leena Laukkanen, Annika Kotovuori, Mirka Reinman, Tero Satomaa, Kaija Alfthan, Saara Laitinen, Kristiina Takkinen, Jarkko Räbinä, and Leena Valmu. BioResearch Open Access. doi:10.1089/biores.2013.0026.

All opinions are moderated before being included (to stop spam). We reserve the right to amend opinions where we deem necessary.

Please note: If no author information is provided, the source is cited instead.

Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.

If you write about specific medications or operations, please do not name health care professionals by name.


Share this post:

If you are a possible stem cell patient, find ways to get a stem cell cure to have much better health and youthfulness

If you're a medical doctor and would like to learn and incorporate various stem cell treatments into your medical practice, be sure to get the proper stem cell medical training


Recent Posts