Future blindness cure? Stem cell success in lab

Jul 23rd, 2013 · Comments Off

Featured Article
Academic Journal
Main Category: Eye Health / Blindness
Also Included In: Stem Cell Research
Article Date: 22 Jul 2013 – 7:00 PDT

He says:


According to researchers, the loss of photoreceptors in the eye is a leading cause of sight loss in degenerative eye diseases such as retinitis pigmentosa, diabetes-related blindness and age-related macular degeneration.

Prof. Ali explains:

Magnificent news, mothers cells have great potential to cure many diseases that have minimized the quality of life for some people, the case that has surprised me in China is experimenting with a patient with limited mobility, making improvements with other treatments never come to get. still a long way to go and can not forget the opposition of religion to these experiments

“That means we have got room to think about a human trial and repeat all this using human embryonic stem cells, and investigate whether we can repair the retina in conditions in which blindness is caused by loss of photoreceptor cells .”

The need for photoreceptor transplantations

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The cells integrated into the existing retina in the mice and formed the required nerve connections that transmit visual information to the brain.

The researchers injected around 200,00 of the artificially grown cells into the retinas of the night-blind mice.

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Scientists are one step closer to curing blindness, after they carried out the first successful transplant of light-sensitive photoreceptor cells from a synthetic retina that was grown from embryonic stem cells.

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However, the researchers say that this method of transplantation would “not be practical for the thousands of patients in need of treatment.”

Written by Honor Whiteman

How was the synthetic retina grown?

The study, published in the journal Nature Biotechnology, shows embryonic stem cells could potentially be used to provide an “unlimited supply of healthy photoreceptors for retinal cell transplantations to treat blindness in humans.”

From this, the scientists were able to grow the synthetic retinas “in a dish” which contain all the nerve cells need to provide sight.

Does that mean that every time I scratch my nose, you can accuse me of a mini-genocide of potential babies? Besides, if your ‘God’ is so great, wouldn’t He already know not to put souls in the laboratory stem-cell clumps? LOGIC!!!

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The researchers add that nerve connections (synapses) developed, meaning that the transplanted cells had the ability to connect with the existing connections within the retina.

“What we have been able to do is build on work of a Japanese group from a study a couple of years ago, in order to make a synthetic retina from embryonic stem cells. We have adapted that and we have shown for the first time that we can use embryonic stem cells to make a retina in a dish.”

No more “three blind mice”

“This now means we have a cell source. This has all been done with mouse embryonic stem cells, but if we do it with human embryonic stem cells then we can do this for the first time using an embryonic stem cell source.”

Prof. Ali adds:

“We have been working on trying to find ways of repairing the retina by transplanting photoreceptor cells, and we have demonstrated proof of concept of that development. They are not stem cells, they are not fully mature photoreceptor cells, but they are immature photoreceptor cells.”

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Back then, the researchers said: “We are hopeful that we will soon be able to replicate this success with photoreceptors derived from embryonic stem cells and eventually to develop human trials.”

Photoreceptors are light-sensitive nerve cells found in the retina of the eye. There are two types of photoreceptors – rods and cones.

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America can lead the way towards amazing cures for a wide variety of diseases and injuries. However, religious lunacy is stunting that development, causing real future harm, future deaths and future misery as a result of the delay. You should be ASHAMED…

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Future blindness cure? Stem cell success in lab

The researchers say the new technique was developed using 3D culture and differentiation of mouse embryonic stem cells, a method recently developed in Japan.


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“There are a number of ways that we can use this research to develop ways of treating blindness through gene therapy and artificial retinas. This is a very exciting approach because it has the ability to restore vision in patients who have very little vision, and the main cause of this in the developing world is loss of photoreceptors. Currently there is no treatment for that.”

Researchers from University College London (UCL) and Moorfields Eye Hospital in the UK, transplanted the photoreceptor cells in to night-blind mice and found that the cells developed normally.

APA

The cones provide the eye’s color sensitivity. The rods are not sensitive to color, but are more sensitive to light than the cones and are particularly important for providing the ability to see in the dark.


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Great news – stem cell to cure blindness

posted by Andrés on 22 Jul 2013 at 3:06 pm

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Religon poisons EVERYTHING, and this is a concrete example of how REAL harm comes from absorbing unproven fossilized mythology.


Retinitus pigmentosa

posted by lorraine a on 22 Jul 2013 at 8:22 am

Prof. Ali says that it will be a few years before this research will be used within a human trial, but the team have already started working with human embryonic stem cells.

Whiteman, Honor. “Future blindness cure? Stem cell success in lab.” Medical News Today. MediLexicon, Intl., 22 Jul. 2013. Web.
22 Jul. 2013. <http://www.medicalnewstoday.com/articles/263749.php>


Religious have another reason to be ashamed

posted by Peter A on 22 Jul 2013 at 8:13 am

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Last year, the team conducted research that involved transplanting photoreceptors into mice suffering from retinal degeneration, using cells taken from healthy mice with normal sight.

The study reports that three weeks after transplantation, the cells from the synthetic retina had “moved and integrated” within the the mice retina and began to look like “normal mature rod cells,” which continued to be present after six weeks.

Professor Robin Ali, of the Institute of Ophthalmology at UCL and Moorfields Eye Hospital, told Medical News Today:

so pleased to hear that the stem cell experiments are progressing hopefully they will progress enough and quickly so that my best friend does not loose her sight completeley


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Retinal precursor cells were grown using the 3D culture method and they were closely compared to normally developed cells, with the researchers noting different stages of development.

MLA

This is yet another example of how the religious need to advance into the 21st century and stop blocking stem-cell research. A 150-cell clump is NOT a baby with a soul! With modern technology, ANY cell in the body can soon be turned into a baby.

“Much of this work has been done in mice in the past. Photoreceptor precursor cells taken from the developing mouse retina and pumped into adult mice shows that this can be effective in restoring vision for the mice that lack vision. This really gave the framework for our translation program. To make it practical, we needed to find a cell source from which we can get these photoreceptor precursors.”

The researchers also carried out tests to ensure that the genes being expressed by the two types of cells were “biologically equivalent” to each other.


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